A method is suggested for determining vascular resistance from the blood flow in the test vascular bed and in the shunt tube that is invariable in length and diameter, paralleled to this bed. In conformity with Hagen-Poiselles's equations, the viscosity component dependent on the composition and the temperature of blood should be omitted in the results obtained by the formula (Formula: see text) where Rv -- vascular resistance; Qs and Qv -- blood flow in the shunt tube and in the vascular bed; Rs -- resistance of the shunt tube calculated according to Poiselle's formula from the shunt parameters and the viscosity index equal to 1 centipoise. At the same time the viscous-rheological component of the resistance closely related to the anatomic functional properties of the vascular network should not be replaced. In contradistinction to the general resistance, this index is designated as specific vascular resistance.