
pmid: 7390275
handle: 11568/246037
Human acid-acetone placental powder (PP) has corticotrophin-like and beta-endorphin(beta-EP)-like activity. In a beta-EP radioimmunoassay the PP showed a potency of 4.82 ng/mg protein. In Sephadex G-75 filtration and high pressure liquid chromatography, the beta-EP-like activity of PP was found in the corresponding chromatographic fractions as standard beta-EP. The PP tested for opiate activity in a radioreceptor assay showed a dilution curve parallel to that of synthetic beta-EP.
Radioligand Assay, Pregnancy, Placenta, Chromatography, Gel, Radioimmunoassay, Humans, Female, Endorphins, Chromatography, High Pressure Liquid
Radioligand Assay, Pregnancy, Placenta, Chromatography, Gel, Radioimmunoassay, Humans, Female, Endorphins, Chromatography, High Pressure Liquid
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