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Hal
Article . 1981
Data sources: Hal
https://pubmed.ncbi.nlm.nih.go...
Article . 1982
Data sources: Europe PubMed Central
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Albendazole : a comparison of relay embryotoxicity with embryotoxicity of individual metabolites.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1981 English Journal:Annales de recherches veterinaires. Annals of veterinary research, volume 12 (issn: 0003-4193, Copyright policy )
Authors: Delatour, P.; Parish, R.C.; Gyurik, R.J.;

pmid: 7342833

Albendazole : a comparison of relay embryotoxicity with embryotoxicity of individual metabolites.

Abstract

By using an experimental model compound (Albendazole, an anthelmintic) the authors compared two methodologies for the toxicological evaluation of bovine hepatic residues. Toxicity was not demonstrated for bovine hepatic residues in a relay embryotoxicity study in the rat. On the other hand, both albendazole and its sulfoxide metabolite produce embryotoxic effects in this rat model. These different results are discussed and explained by considerations related to the no effect levels and the chemical nature of the different types of residues.

Keywords

[SDV.IMM] Life Sciences [q-bio]/Immunology, [SDV.BA] Life Sciences [q-bio]/Animal biology, Chemical Phenomena, Drug Evaluation, Preclinical, [SDV.GEN.GA] Life Sciences [q-bio]/Genetics/Animal genetics, [SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Albendazole, Pregnancy, Animals, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.BC] Life Sciences [q-bio]/Cellular Biology, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, Fetal Death, Anthelmintics, Abnormalities, Drug-Induced, Rats, Inbred Strains, Diet, Rats, Chemistry, Liver, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Benzimidazoles, Cattle, Female

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
41
Average
Top 10%
Average
Green