In vitro activity of thienamycin.

P M, Shah

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Methods and Findings...arrow_drop_down

Methods and Findings in Experimental and Clinical Pharmacology

Article . 1982

Data sources: Europe PubMed Central

In vitro activity of thienamycin.

descriptionPublicationkeyboard_double_arrow_right Article 20 Apr 1982 English Journal:Methods and findings in experimental and clinical pharmacology, volume 3 (issn: 0379-0355,

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Authors: P M, Shah;

pmid: 7329164

In vitro activity of thienamycin.

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Abstract

The in vitro activity of thienamycin was determined simultaneously in Müller-Hinton broth and peptone broth. Minimum inhibitory and bactericidal concentrations were compared to those of 4 aminoglycosides and 3 cefalosporins. The activity of thienamycin against gram-negative aerobic bacterial was influenced by the media. Peptone broth gave the lowest MICs and MBCs. Concentrations less than or equal to 8 mcg thienamycin/ml peptone broth inhibited 354 out of 382 strains tested.

Keywords

Aminoglycosides, Bacteria, Lactams, Thienamycins, Microbial Sensitivity Tests, Anti-Bacterial Agents, Cephalosporins

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