Effective immunization of lambs against enterotoxaemia.
Copyright policy )Effective immunization of lambs against enterotoxaemia.
In contrast to adult sheep, 2- to 3-month-old lambs do not respond well to a single injection of Clostridium perfringens Type D oil adjuvant epsilon toxoid. This unresponsiveness can be overcome, however, by administering 2 injections of oil adjuvant vaccine or one injection of oil adjuvant followed 4 weeks later by an injection of alum-precipitated toxoid. The latter procedure evokes protective antitoxin levels which persist for 8 months, and a booster injection of alum-precipitated toxoid given at this stage results in an immunity which lasts for at least 1 year.
- University of Pretoria South Africa
Clostridium, Male, Sheep, Time Factors, Age Factors, Sheep Diseases, Lambs -- Vaccination, Toxoids, Enterotoxaemia, Antibody Formation, Bacterial Vaccines, Veterinary medicine -- South Africa, Clostridium Infections, Animals, Immunization Schedule, Enterotoxemia
Clostridium, Male, Sheep, Time Factors, Age Factors, Sheep Diseases, Lambs -- Vaccination, Toxoids, Enterotoxaemia, Antibody Formation, Bacterial Vaccines, Veterinary medicine -- South Africa, Clostridium Infections, Animals, Immunization Schedule, Enterotoxemia
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