Leukapheresis and granulocyte transfusion.
Copyright policy )Leukapheresis and granulocyte transfusion.
Newer cell separators can collect more PMN, especially using macromolecular agents and steroid stimulation of donors. Proper indications for PMN transfusion are severe neutropenia and sepsis, or certain localized infections, when prolonged marrow aplasia is expected. Optimal dosage is at least 2 x 10(10) PMN per day, probably more. There is a need for more accurate definition of clinical indications for PMN support, for still greater PMN yields from leukapheresis, and for better PMN storage capability.
Blood Specimen Collection, Neutropenia, Macromolecular Substances, Histocompatibility Testing, Anticoagulants, Transfusion Reaction, Blood Donors, Bacterial Infections, Leukocyte Count, Dogs, Adrenal Cortex Hormones, Blood Preservation, Blood Group Incompatibility, Animals, Humans, Blood Transfusion, Clinical Competence, Leukapheresis, Granulocytes
Blood Specimen Collection, Neutropenia, Macromolecular Substances, Histocompatibility Testing, Anticoagulants, Transfusion Reaction, Blood Donors, Bacterial Infections, Leukocyte Count, Dogs, Adrenal Cortex Hormones, Blood Preservation, Blood Group Incompatibility, Animals, Humans, Blood Transfusion, Clinical Competence, Leukapheresis, Granulocytes
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