
A highly active glutathione peroxidase (80% of which is localized in the water-soluble fraction) was detected in frog eye pigment epithelium tissue. It was shown that more than 75% of the glutathione peroxidase activity of the pigment epithelium tissue is bound to the Se-dependent enzyme. The Km values for glutathione and tret-butyl hydroperoxide were determined. It was found that Se, being a constituent of the melanoprotein granules, is not coupled to glutathione peroxidase.
Glutathione Peroxidase, Kinetics, Selenium, Peroxidases, Rana temporaria, Animals, Pigment Epithelium of Eye
Glutathione Peroxidase, Kinetics, Selenium, Peroxidases, Rana temporaria, Animals, Pigment Epithelium of Eye
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