[Delta-antigen in hepatitis B].

E, Stöcklin; F, Gudat; L, Bianchi; M, Schmid; G A, Stalder

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Article . 1982

Data sources: Europe PubMed Central

[Delta-antigen in hepatitis B].

descriptionPublicationkeyboard_double_arrow_right Article 19 Jul 1982 German Journal:Schweizerische medizinische Wochenschrift, volume 112 (issn: 0036-7672,

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Authors: E, Stöcklin; F, Gudat; L, Bianchi; M, Schmid; G A, Stalder;

pmid: 6805071

[Delta-antigen in hepatitis B].

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Abstract

Among 571 liver biopsies delta-Ag was found in 10 of 365 HBsAg positive patients (9 with CAH, 1 with CPH). Delta-Ag was demonstrated in nuclei and cytoplasm of liver cells in both cryostat and paraffin sections. Follow-up studies revealed persistence of delta-Ag for as long as 6 years and temporary appearance or loss of Dane particle-associated parameters without a change in the concomitant inflammation. These findings are compatible with the hypothesis that delta-Ag represents a defective viral agent which modulates, by superinfection, the typical viral expression patterns of HBV infection.

Keywords

Hepatitis B Antigens, Hepatitis B virus, Immunoglobulin delta-Chains, Liver, Humans, Hepatitis B, Immunoglobulin Heavy Chains

3 Research products, page 1 of 1

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