Schizophrenic disorders and HLA-DR antigens.
Copyright policy )Schizophrenic disorders and HLA-DR antigens.
HLA-A, -B, and -DR antigens, including supertypic specificities (MT antigens), were studied in Japanese schizophrenic patients. Although frequencies of HLA-A, -B, and MT antigens did not differ significantly between the schizophrenic patients and controls, the frequency of DRw8 in DR locus showed a statistically significant increase in the patients. The authors conclude that DRw8 is a genetic marker of susceptibility to schizophrenia. Inconsistencies in previous reports of antigens could be resolved by examination of the DR locus.
Adult, Genetic Markers, Male, Adolescent, HLA-A Antigens, Histocompatibility Antigens Class II, HLA-DR Antigens, Middle Aged, Asian People, HLA Antigens, HLA-B Antigens, Schizophrenia, Humans, Female
Adult, Genetic Markers, Male, Adolescent, HLA-A Antigens, Histocompatibility Antigens Class II, HLA-DR Antigens, Middle Aged, Asian People, HLA Antigens, HLA-B Antigens, Schizophrenia, Humans, Female
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