[Comparative evaluation of the biogenic amine level of the brain and the ethanol kinetics in the blood of inbred C57B1/6 and CBA mice].
Copyright policy )[Comparative evaluation of the biogenic amine level of the brain and the ethanol kinetics in the blood of inbred C57B1/6 and CBA mice].
The kinetics of ethanol in blood and the levels of serotonin, noradrenaline, and dopamine in the cortex of cerebral hemispheres, hypothalamus, thalamus, and brain stem were studied in male C57C1/6 and CBA mice characterized by predisposition and non-predisposition to the development of experimental alcoholism. C57B1/6 mice characterized by predisposition to the development of experimental alcoholism demonstrated a high level of serotonin and noradrenaline in the hypothalamus and brain stem and high rate of ethanol elimination from the blood. CBA mice non-predisposed to the development of experimental alcoholism were characterized by a low level of serotonin and noradrenaline in the hypothalamus and brain stem and by low rate of ethanol elimination from blood.
Brain Chemistry, Male, Mice, Inbred C57BL, Alcoholism, Biogenic Amines, Kinetics, Mice, Ethanol, Mice, Inbred CBA, Animals, Brain, Humans, Disease Susceptibility
Brain Chemistry, Male, Mice, Inbred C57BL, Alcoholism, Biogenic Amines, Kinetics, Mice, Ethanol, Mice, Inbred CBA, Animals, Brain, Humans, Disease Susceptibility
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