HLA-DB3: population distribution and family studies of a new HLA-D antigen associated with HLA-D antigen associated with HLA-DR4 in Caucasoids.
Copyright policy )HLA-DB3: population distribution and family studies of a new HLA-D antigen associated with HLA-D antigen associated with HLA-DR4 in Caucasoids.
On the basis of studies with 6 HTCs in four different families the new cluster DB3 identified in the 8th Workshop can be considered an established specificity of the HLA-D series. In 112 healthy Caucasoids resident in South East England the frequency of this antigen was 2.6% similar to the frequency found in 142 Caucasoid patients with rheumatoid arthritis. The frequency in 54 unrelated Chinese individuals from Shanghai and of 120 Nigerians was 7.5% and 3%, respectively. All Caucasoid individuals who were DB3 were also DR4 whereas no such association was found in the two other population groups.
- University of Manchester United Kingdom
- University of Manchester United Kingdom
Male, China, HLA-D Antigens, Genes, MHC Class II, Homozygote, Racial Groups, Black People, Nigeria, White People, Pedigree, Asian People, England, HLA-DR4 Antigen, Humans, Female, HLA-DRB3 Chains
Male, China, HLA-D Antigens, Genes, MHC Class II, Homozygote, Racial Groups, Black People, Nigeria, White People, Pedigree, Asian People, England, HLA-DR4 Antigen, Humans, Female, HLA-DRB3 Chains
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