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Field evaluation of ELISA using Wuchereria bancrofti mf ES antigen for bancroftian filariasis.

Authors: B C, Harinath; A, Malhotra; S N, Ghirnikar; S D, Annadate; V P, Isaacs; M S, Bharti;

Field evaluation of ELISA using Wuchereria bancrofti mf ES antigen for bancroftian filariasis.

Abstract

An enzyme-linked immunosorbent assay using Wuchereria bancrofti microfilarial excretory-secretory antigen was used in field studies to screen blood samples collected on filter-paper from persons residing in areas endemic for bancroftian filariasis. This assay system, when compared with examination of night wet blood smears for microfilariae, gave a relative sensitivity of 98% and a relative specificity of 86%. Daytime blood samples can also be used in this test, which can thus replace tedious examination of night blood samples in field surveys in endemic areas.

Keywords

Immunoenzyme Techniques, Blood Specimen Collection, Antigens, Helminth, Humans, Enzyme-Linked Immunosorbent Assay, Wuchereria bancrofti, Wuchereria, Filariasis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
14
Average
Top 10%
Average
Published in a Diamond OA journal