
Human retinoblastoma contains clusters of cells immunoreactive for methionine-enkephalin and methionine-enkephalin-arginine-phenylalanine. Some tumour cells also exhibited methionine-enkephalin-arginine-glycine-leucine-like immunoreactivity. The results are in agreement with those obtained with similar testing of neuroblastoma cell cultures. It is concluded that some human retinoblastoma cells are capable of synthesizing preproenkephalin A or parts of this molecule.
Enkephalin, Methionine, Eye Neoplasms, Retinoblastoma, Fluorescent Antibody Technique, Infant, Enkephalins, Microscopy, Fluorescence, Humans, Female, Protein Precursors, Cells, Cultured
Enkephalin, Methionine, Eye Neoplasms, Retinoblastoma, Fluorescent Antibody Technique, Infant, Enkephalins, Microscopy, Fluorescence, Humans, Female, Protein Precursors, Cells, Cultured
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