[Alternative complement pathway].
The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and regulation of the pathway; involvement of the alternative pathway in human diseases.
Properdin, Complement Pathway, Alternative, Complement C3, Complement C3-C5 Convertases, Infections, Complement Factor H, Antibody Formation, Complement C3b Inactivator Proteins, Humans, Complement Factor D, Complement Activation, Complement Factor B
Properdin, Complement Pathway, Alternative, Complement C3, Complement C3-C5 Convertases, Infections, Complement Factor H, Antibody Formation, Complement C3b Inactivator Proteins, Humans, Complement Factor D, Complement Activation, Complement Factor B
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