<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Effects of arginine-8-vasopressin and 1-deamino-8-D-arginine-vasopressin on ACTH secretion in rats.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983 Hungary English Journal:Endocrinologia experimentalis, volume 17 (issn: 0013-7200,

Authors: László Ferenc; Janáky Tamás; Julesz János; Kárteszi Mihály; Makara Gábor; Stark Ervin;

pmid: 6309504

Effects of arginine-8-vasopressin and 1-deamino-8-D-arginine-vasopressin on ACTH secretion in rats.

- Summary
- Subjects
- Related research
  (1)
- Metrics

Abstract

The corticotropin-releasing effect of arginine-8-vasopressin (AVP) has been compared to that of 1-deamino-8-D-arginine-vasopressin (dDAVP) in male rats of R-Amsterdam strain. AVP increased the level of ACTH and corticosterone in the peripheral blood in a dose-dependent manner. In contrast to AVP, a very potent antidiuretic agent dDAVP which is devoid of pressor activity had no effect on ACTH release and did not stimulate the secretion of corticosterone. It is concluded that CRF activity of vasopressin in vivo is related to its pressor activity. These data are in agreement with the previous findings of these authors demonstrating that dDAVP shows a very low affinity for vasopressin receptors of the cell membranes in the adenohypophysis.

Country

Hungary

Related Organizations

University of Szeged
Hungary

Keywords

Male, Receptors, Vasopressin, Receptors, Cell Surface, Rats, Arginine Vasopressin, Adrenocorticotropic Hormone, Pituitary Gland, Anterior, Animals, Deamino Arginine Vasopressin, 03.02. Klinikai orvostan, Corticosterone

1 Research products, page 1 of 1

In vitro desensitization of isolated nephron segments to vasopressin.
1990IsAmongTopNSimilarDocuments

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	4
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average