[The hypothalamo-hypophyseal system: the role of calcium ions].

A, Lasco; N, Barbera; O, Ciraolo; V, Nicita-Mauro

Found an issue? Give us feedback

https://pubmed.ncbi....arrow_drop_down

https://pubmed.ncbi.nlm.nih.go...

Article . 1983

Data sources: Europe PubMed Central

[The hypothalamo-hypophyseal system: the role of calcium ions].

descriptionPublicationkeyboard_double_arrow_right Article 21 Oct 1983 Italian Journal:Bollettino della Societa italiana di biologia sperimentale, volume 59 (issn: 0037-8771,

Copyright policy )

Authors: A, Lasco; N, Barbera; O, Ciraolo; V, Nicita-Mauro;

pmid: 6309195

[The hypothalamo-hypophyseal system: the role of calcium ions].

- Summary
- Subjects
- Metrics

Abstract

The Authors investigated the effects of Verapamil a calcium antagonist substance upon the pituitary response to several secretogogus agents in ten male healthy subjects in order to elucidate the calcium role in the regulation of the hypothalamic pituitary function. As a consequence of Verapamil administration (5 mg iv) a significant hyporesponsiveness of FSH and LH to GnRH (100 micrograms iv) of TSH to TRH (200 gamma iv) and of ACTH to insulin induced hypoglycemia was observed. Prolactin response to TRH (200 gamma iv) was not modified by Verapamil treatment. The Authors concluded emphasizing the importance of Ca++ in the modulation of diencephalic pituitary activity.

Keywords

Adult, Male, Hypothalamo-Hypophyseal System, Adolescent, Luteinizing Hormone, Gonadotropin-Releasing Hormone, Adrenocorticotropic Hormone, Verapamil, Humans, Insulin, Calcium, Follicle Stimulating Hormone, Thyrotropin-Releasing Hormone

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average