Potency testing of killed polio vaccine in rats.
Copyright policy ) van Steenis, G; van Wezel, AL; Sekhuis, VM;
Potency testing of killed polio vaccine in rats.
Various laboratory animal species were considered for testing the potency of killed poliovaccine. The rat appeared most suitable for obtaining quantitative information by measuring the titre of the antibody response. There was, in general, a good correlation between antibody response in rats and D-antigen titre. This relationship appeared less clear for heat-degraded or long-stored vaccines.
Netherlands
Virulence, Guinea Pigs, Rats, Inbred Strains, Rats, Poliovirus, Poliovirus Vaccine, Inactivated, Antibody Formation, Animals, Humans, Antigens, Viral
Virulence, Guinea Pigs, Rats, Inbred Strains, Rats, Poliovirus, Poliovirus Vaccine, Inactivated, Antibody Formation, Animals, Humans, Antigens, Viral
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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