[T-lymphocytes with a receptor for the immunoglobulin Fc fragment in the blood of multiple sclerosis patients].
Copyright policy )[T-lymphocytes with a receptor for the immunoglobulin Fc fragment in the blood of multiple sclerosis patients].
In 12 multiple sclerosis patients and 15 healthy subjects the suppressor activity in vitro by the method of Shou et al. was determined parallelly with the number of T-lymphocytes with the receptor for the Fc fragment of immunoglobulin G (TG lymphocytes). In healthy subjects a correlation (p less than 0.05) was demonstrated between the suppressor activity of lymphocytes in vitro and the number of TG lymphocytes in the peripheral blood. On the other hand, in multiple sclerosis patients a decrease was observed frequently in the suppressor activity of these cells in vitro (especially during exacerbation of the disease) while the number of TG lymphocytes in the peripheral blood was normal or raised sometimes. Different causes of the this phenomenon in multiple sclerosis are discussed.
Adult, Male, Multiple Sclerosis, T-Lymphocytes, In Vitro Techniques, Middle Aged, T-Lymphocytes, Regulatory, Immunoglobulin Fc Fragments, Chronic Disease, Concanavalin A, Humans, Female
Adult, Male, Multiple Sclerosis, T-Lymphocytes, In Vitro Techniques, Middle Aged, T-Lymphocytes, Regulatory, Immunoglobulin Fc Fragments, Chronic Disease, Concanavalin A, Humans, Female
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