
Author resume the most important stages of the antitubercular struggle. Then they consider the action mechanisms of single drugs, often not well known, such the action mechanism of pyrazinamide. At present, the criteria of effectiveness, tolerance, availability and economy allow to use rationally and not arbitrarily the antitubercular drugs and these criteria also assure the best therapeutic results.
Antimetabolites, Antitubercular Agents, DNA, Isoniazid, Folic Acid Antagonists, Humans, RNA, Ethionamide, Rifampin, Tuberculosis, Pulmonary, Ethambutol
Antimetabolites, Antitubercular Agents, DNA, Isoniazid, Folic Acid Antagonists, Humans, RNA, Ethionamide, Rifampin, Tuberculosis, Pulmonary, Ethambutol
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
