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Archives of Pathology & Laboratory Medicine

Article . 1982

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Amylase in fallopian tube and serous ovarian neoplasms: immunohistochemical localization.

descriptionPublicationkeyboard_double_arrow_right Article 25 Feb 1982 English Journal:Archives of pathology & laboratory medicine, volume 106 (issn: 0003-9985,

Authors: D E, Bruns; S E, Mills; J, Savory;

pmid: 6172088

Amylase in fallopian tube and serous ovarian neoplasms: immunohistochemical localization.

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Abstract

We studied the cellular localization of amylase in normal Fallopian tubes and serous ovarian neoplasms using an indirect immunoperoxidase technique. The primary antiserum was against human pancreatic amylase, and was found to inhibit ovarian tumor amylase as well. Amylase was present in normal endosalpingeal epithelium and in the epithelial cells of benign, borderline, and malignant serous ovarian tumors. A mucinous cystadenoma was also studied and contained no amylase. This localization suggests that amylase production by serous ovarian neoplasms reflects the endosalpingeal differentiation of these tumors. Antibody to amylase may be potentially useful in distinguishing serous ovarian tumors from other forms of ovarian neoplasia.

Keywords

Ovarian Neoplasms, Histocytochemistry, Cystadenoma, Cross Reactions, Epithelium, Diagnosis, Differential, Immunoenzyme Techniques, Amylases, Humans, Female, Pancreas, Fallopian Tubes

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	42
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%