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An IgE inhibition assay for the detection of allergen specific IgE.

Authors: Sweeney, M. J.; Kay, C.; Klotz, L. R.; Klotz, S. D.;

An IgE inhibition assay for the detection of allergen specific IgE.

Abstract

A method for the detection of specific IgE in human serum is described, using a modified radioimmune assay termed the Inhibition Assay Technique (IAT) The technique is based on the ability of specific IgE to bind with allergen. The difference in total IgE before incubation with the allergen and after incubation with the allergen gives a relative concentration of specific IgE to that particular allergenic substance. The assay has been shown to correlate with both the intradermal skin test as well as the standard RAST now used to determine specific IgE.

Country
United States
Related Organizations
Keywords

Epitopes, Radioallergosorbent Test, Allergy, Humans, Binding Sites, Antibody, Allergens, Immunoglobulin E, Radioimmunosorbent Test, Skin Tests

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    4
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    influence
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Powered by OpenAIRE graph
Found an issue? Give us feedback
citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Top 10%
Top 10%
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