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[Primary biliary liver cirrhosis].

Authors: S, Sailer; G, Lanzer;

[Primary biliary liver cirrhosis].

Abstract

Primary biliary cirrhosis, or chronic destructive nonsuppurative cholangitis, is a condition of chronic cholestasis, in which small intrahepatic bile ducts in the portal zones of the liver become progressively destroyed. The etiology of primary biliary cirrhosis is unknown, but the observation of (a) mitochondrial antibody, (b) elevated serum levels of IgM and (c) circulating immune complexes and (d) impaired lymphocyte transformation (- cooperation) strongly suggest, that disordered immune responses play a major role in the initiation or progression of this chronic hepatic lesion.

Keywords

Antigens, Bacterial, Cholestasis, Liver Cirrhosis, Biliary, Bile Canaliculi, Antigen-Antibody Complex, T-Lymphocytes, Helper-Inducer, gamma-Glutamyltransferase, Cross Reactions, Alkaline Phosphatase, T-Lymphocytes, Regulatory, Antibodies, Autoimmune Diseases, Mitochondria, Immunoglobulin M, Granuloma, Giant Cell, Antibody Formation, Humans

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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