[Various biological characteristics of Sindbis virus].

Name: [Various biological characteristics of Sindbis virus].
Keywords: Mice, Cytopathogenic Effect, Viral, Species Specificity, Temperature, Animals, Humans, Chick Embryo, Interferons, Sindbis Virus, Virus Replication

PUGLIESE, Agostino; BIGLINO, Alberto; VALPREDA A; TOVO, Pier Angelo

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Archivio Istituzionale della Ricerca (AperTO) - Università di Torino

Article . 1983

Data sources: Archivio Istituzionale della Ricerca (AperTO) - Università di Torino

https://pubmed.ncbi.nlm.nih.go...

Article . 1985

Data sources: Europe PubMed Central

[Various biological characteristics of Sindbis virus].

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983 Italian Journal:Giornale di batteriologia, virologia ed immunologia, volume 76 (issn: 0390-5462,

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Authors: PUGLIESE, Agostino; BIGLINO, Alberto; VALPREDA A; TOVO, Pier Angelo;

pmid: 6085056

handle: 2318/31809

[Various biological characteristics of Sindbis virus].

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Abstract

The hemagglutinating activity of Sindbis virus on untreated or tripsinized blood red cells of some animal species was assessed. In some cases tripsinization increases the red cell sensitivity to viral hemagglutinin. Interferon (IFN) production induced by Sindbis virus on human WISH, mouse L-929 and chicken FEP cells was similar in all three cases. The effects of the temperature on virus replication were studied. Optimal growth was seem to take place at 37 degrees C. These data suggest that the viral pathogenic effect in humans in contrast to the asymptomatic infection in reservoirs is not related to differences in IFN production, but could be due to differences in host body temperature.

Related Organizations

University of Turin
Italy

Keywords

Mice, Cytopathogenic Effect, Viral, Species Specificity, Temperature, Animals, Humans, Chick Embryo, Interferons, Sindbis Virus, Virus Replication, Hemagglutination, Viral, Cell Line

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