
pmid: 5538996
pmc: PMC1484037
Tightly coupled models for the sodium and potassium conductance changes, in which the potassium "on" process is intimately related to the sodium "on" and "off" processes, are studied. It is shown that such coupled models are incapable of simultaneously showing the observed effects of conditioning potentials on sodium inactivation and on the translation of the potassium conductance in time. It is concluded that the primary mechanisms for the sodium and potassium channels are probably independent.
Kinetics, Cell Membrane, Models, Neurological, Sodium, Electric Conductivity, Potassium, Nerve Fibers, Myelinated, Mathematics
Kinetics, Cell Membrane, Models, Neurological, Sodium, Electric Conductivity, Potassium, Nerve Fibers, Myelinated, Mathematics
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