Biological standardization of potency testing of diphtheria-tetanus-pertussis vaccines.

Z, Csizér; J, Zsidai

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Article . 1980

Data sources: Europe PubMed Central

Biological standardization of potency testing of diphtheria-tetanus-pertussis vaccines.

descriptionPublicationkeyboard_double_arrow_right Article 18 Dec 1980 English Journal:Annales immunologiae Hungaricae, volume 19 (issn: 0570-1708,

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Authors: Z, Csizér; J, Zsidai;

pmid: 552225

Biological standardization of potency testing of diphtheria-tetanus-pertussis vaccines.

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Abstract

Active protection tests were introduced for the potency testing of the toxoid components of the DTP vaccine. The standardization of these tests is described, with special attention on WHO requirements. A freeze-dried, adsorbed DTP vaccine was prepared for use under tropical or subtropical conditions. The potency testing of the components of this vaccine is presented in this paper.

Keywords

Male, Pertussis Vaccine, Hungary, Mice, Diphtheria Toxoid, Guinea Pigs, Immunity, Tetanus Toxoid, Animals, Female

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