
A total of 100 patients were tested with different mucolytic agents. In patients with acute obstructive airway disease pancreatic dornase and acetyl-L-cysteine (Airbron) showed excellent mucolytic activity. With Alevaire and Ascoxal we were unable to demonstrate any mucolytic action. Proteolytic enzymes were not tested in view of their uncontrollable action on alveolar epithelium and the recent observation that metaplasia of the bronchial mucosa may be produced by these enzymes.
Adult, Clinical Trials as Topic, Deoxyribonucleases, Sodium, Pneumonia, Streptodornase and Streptokinase, Middle Aged, Asthma, Acetylcysteine, Bronchiectasis, Airway Obstruction, Bicarbonates, Pulmonary Emphysema, Chronic Disease, Chymotrypsin, Humans, Bronchitis, Aged, Expectorants, Peptide Hydrolases
Adult, Clinical Trials as Topic, Deoxyribonucleases, Sodium, Pneumonia, Streptodornase and Streptokinase, Middle Aged, Asthma, Acetylcysteine, Bronchiectasis, Airway Obstruction, Bicarbonates, Pulmonary Emphysema, Chronic Disease, Chymotrypsin, Humans, Bronchitis, Aged, Expectorants, Peptide Hydrolases
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