Prevention of sciatic injection neuropathy can best be accomplished by teaching that the injection should be made into the gluteal mass in the upper outer quadrant rather than the buttock, and that the needle should be introduced in a plane perpendicular to the surface of the bed when the patient is lying prone. Failing prevention, one must strive for early and correct diagnosis, especially in infants, and carry out exploration with internal and external neurolysis if there is no evidence of improvement within two to three months.