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A double-blind crossover trial of fenoprofen calcium versus acetylsalicylic acid (aspirin) and placebo in 10 outpatients with active rheumatoid arthritis, is reported. Both fenoprofen and aspirin were found to be similarly effective agents in rheumatoid arthritis with an average dose of 2,1 g fenoprofen compared with 4,5 g aspirin. No significant changes in selected laboratory tests were observed with either drug. The patients reported twice as many side-effects with aspirin; in fact, no drug-related side-effects could be attributed to fenoprofen itself. It is concluded that fenoprofen is a valuable and safe addition to the rheumatologist's armamentarium.S. Afr. Med. J., 48, 899 (1974).
Adult, Male, Analgesics, Clinical Trials as Topic, Dextropropoxyphene, Aspirin, Phenyl Ethers, Anti-Inflammatory Agents, Middle Aged, Blood Urea Nitrogen, Enzymes, Arthritis, Rheumatoid, Placebos, Humans, Female, Propionates, Aged
Adult, Male, Analgesics, Clinical Trials as Topic, Dextropropoxyphene, Aspirin, Phenyl Ethers, Anti-Inflammatory Agents, Middle Aged, Blood Urea Nitrogen, Enzymes, Arthritis, Rheumatoid, Placebos, Humans, Female, Propionates, Aged
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 8 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |