High-output stoma, which often occurs after ileostomy, results in substantial enteric losses that can lead to dehydration, electrolyte disturbances, and malnutrition. Management requires a multidisciplinary approach including rehydration, tailored nutrition, and therapies aimed at reducing stoma output. First-line management is restoration of intravascular volume with sodium-containing fluids, followed by evaluation and treatment of underlying causes such as infection or partial stricture. Regular monitoring of stoma output and urine output is essential to prevent long-term complications such as renal failure. Control of the condition is, in the majority of cases, achieved through rehydration, dietary measures, and antisecretory/antimotility agents.