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Eurosurveillance
Article . 2026
Data sources: Europe PubMed Central
Claim

Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025.

descriptionPublicationkeyboard_double_arrow_right Article 03 Jun 2026 English Journal:Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, volume 31 (issn: 1560-7917, Copyright policy )
Authors: Ying, Shen; Daitao, Zhang; Zhaomin, Feng; Chunna, Ma; Weixian, Shi; Wei, Duan; Jia, Li; +12 Authors

pmid: 41540926

pmc: PMC12811710

Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025.

Abstract

During the early 2025/26 influenza season, influenza A(H3N2) subclade K rapidly predominated in Beijing, China. Using a test-negative design, we estimated influenza vaccine effectiveness (VE) among influenza-like illness outpatients tested between September and December 2025. Among 9,579 participants, sequencing of 316 randomly selected A(H3N2)-positive samples showed 84.8% were subclade K, and antigenic analysis of 65 viruses indicated antigenic divergence. Despite this, adjusted VE against laboratory-confirmed influenza was 41.3% (95% CI: 29.2 to 51.3), indicating moderate protection during this subclade K-dominated season.

Related Organizations
Keywords

Male, Adult, China, Adolescent, Influenza A Virus, H3N2 Subtype, Vaccination, Vaccine Efficacy, Infant, Middle Aged, Young Adult, Influenza Vaccines, Beijing, Child, Preschool, Influenza, Human, Humans, Female, Seasons, Child, Antigens, Viral

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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Published in a Diamond OA journal