The Bronchiectasis & NTM Association established a network of specialized care centers with unique skills in the diagnosis and management of patients with bronchiectasis (BE) and/or infection with nontuberculous mycobacteria (NTM). The mission of the network is to reduce the time to diagnosis and support high-quality care for patients affected by these conditions. This was intended to address the rising incidence and prevalence of people with BE and/or NTM infection. As part of this care center network, there is development of standards of care based upon consensus agreement of experts. This position paper addresses the structure of a care center, including the members of a multidisciplinary core team, essential partners for more common complications of disease, and the necessary supportive staff to provide comprehensive care for patients with BE and/or NTM infection. Through review of the literature and expert consensus, this is intended to guide the development and improvement of care centers.