In a rabbit study a new material for conjunctival reconstruction was compared to lyophilized, amniotic membranes, which have been used for a long time. Standardized conjunctival defects were covered with thin, heterologous, glutaraldehyde-treated pericardium in one group, while in the other group lyophilized amnion grafts were used. In addition, conventional running suture fixation of the patches was compared to a fibrin sealing technique. The macroscopic findings during the follow-up period and the histological results are reported.