3-hydrazinopyridazine derivatives as inhibitors of the copper containing amine oxidases.
Copyright policy )3-hydrazinopyridazine derivatives as inhibitors of the copper containing amine oxidases.
A series of 3-hydrazine derivatives with antihypertensive properties were studied as inhibitors of the copper containing amine oxidases. All the compounds with a free hydrazino group were found to be strong-non-competitive inhibitors. Some of them had an inhibitory activity of the same order as that of hydralazine.
Oxidoreductases Acting on CH-NH Group Donors, Monoamine Oxidase Inhibitors, Swine, Mitochondria, Liver, Benzylamine Oxidase, Rats, Pyridazines, Pregnancy, Animals, Humans, Female, Indicators and Reagents, Amine Oxidase (Copper-Containing), Antihypertensive Agents, Copper
Oxidoreductases Acting on CH-NH Group Donors, Monoamine Oxidase Inhibitors, Swine, Mitochondria, Liver, Benzylamine Oxidase, Rats, Pyridazines, Pregnancy, Animals, Humans, Female, Indicators and Reagents, Amine Oxidase (Copper-Containing), Antihypertensive Agents, Copper
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