Cervical spondylotic radiculopathy (CSR) seriously affects patients' quality of life and faces clinical treatment dilemmas. The study aimed to evaluate the clinical efficacy of Shujin Tongluo Granules combined with orthopedic techniques in the treatment of CSR of the qi stagnation and blood stasis type. From 2022 to 2024, 96 CSR patients were selected and randomized into two groups. Both groups were treated with traditional Chinese medicine orthopedic manipulation treatment, the study group added Shujin Tongluo granules. Observe and analyse both groups' clinical outcomes, assess the improvement of symptoms, serum levels of pain factors and inflammatory factors and record the incidence of adverse reactions. After treatment, both groups of patients improved. Compared with the control group, the traditional Chinese medicine main symptom, visual analog scale, neck disability index scores, pain factors and inflammatory factors levels in study group patients decreased significantly, while the Japanese orthopaedic associationscores and regulatory oriented motion scores increased significantly. Comparing to control group, the study group had a more clinical treatment effect. Shujin Tongluo granules combined with orthopedic manipulation have a better effect on improving the symptoms of qi stagnation and blood stasis type of CSR, which deserves to be further explored in future clinical trials.