[Detection and interpretation of PD-L1 in urologic neoplasms].
Copyright policy )[Detection and interpretation of PD-L1 in urologic neoplasms].
Immune checkpoint inhibitors targeting PD-1/PD-L1 are gradually being applied in the treatment of advanced urinary system tumors. Immunohistochemical analysis of PD-L1 expression is the most popular method for screening suitable patients for immunotherapy and predicting therapeutic efficacy. The current application status of PD-L1 detection for urinary system tumors (mainly urothelial carcinoma), methods of the different antibody tests and the precautions, challenges and solutions in the interpretation of immunostaining were summarized in this review.
- Peking University China (People's Republic of)
- University of Hong Kong - Shenzhen Hospital China (People's Republic of)
Urologic Neoplasms, Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Biomarkers, Tumor, Humans, Immunotherapy, Immunohistochemistry, Immune Checkpoint Inhibitors, B7-H1 Antigen
Urologic Neoplasms, Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Biomarkers, Tumor, Humans, Immunotherapy, Immunohistochemistry, Immune Checkpoint Inhibitors, B7-H1 Antigen
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!