To investigate the application value of periodontal microsurgery in accelerated osteogenic orthodontics (PAOO).A total of 100 patients with the need of PAOO surgery before orthodontic treatment due to the lack of alveolar bone in the mandibular anterior area were selected and randomly divided into microsurgery group and control group with 50 cases in each group. Preoperative CBCT was used to measure the thickness and height of the alveolar bone as well as the gingival thickness. The gingival recession height was measured using periodontal probe. The pain level of the patients was evaluated immediately, 3, 7 and 14 days after surgery while the wound healing was recorded 14 days after surgery. The aforementioned indexes were recorded again 6 months after surgery. GraphPad Prism 5.0 software package was used for data analysis.The pain level of the microsurgery group were significantly lower than those of the control group at different time points after surgery. All the patients in the microsurgery group achieved healing by first intention 14 days after surgery. In addition, 6 months after surgery, the increase in alveolar bone thickness and the improvement of gingival recession in the microsurgery group were significantly better than those in the control group, thus achieving higher patient satisfaction.Periodontal microsurgery can facilitate the improvement of the surgical effect of PAOO, which has a promising value in the clinical application.