
Strict control of blood glucose was achieved by continuous subcutaneous insulin infusion with a specially adapted Mill Hill Infuser for 3-4 days. This led to normalisation of some of the intermediary metabolites. In a few patients, subcutaneous infusions have been carried out for periods up to 3 months with home monitoring of blood glucose, without infection or lipodystrophy. Short-term improvement of metabolic control was associated with recovery of abnormal renal glomerular permeability to albumin.
Blood Glucose, Islets of Langerhans, Alanine, Diabetes Mellitus, Humans, Insulin, Infusions, Parenteral, Artificial Organs, Feedback
Blood Glucose, Islets of Langerhans, Alanine, Diabetes Mellitus, Humans, Insulin, Infusions, Parenteral, Artificial Organs, Feedback
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