Bactericidal activity of cefazedone.
Copyright policy )Bactericidal activity of cefazedone.
Distinct bactericidal activity of (6R,7R)-7-(2-[3,5-dichloro-4-oxo-1(4H)-pyridyl]-acetamido)-3-([(5-methyl-1,3,4-thiadiazol-2-yl)-thio]methyl)-8-oxo-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, Refosporen) could be demonstrated in 2 Staphylococcus aureus and 3 Escherichia coli strains. The effect was less in 1 strain of Proteus mirabilis. Whereas the activity in serum and bile was higher than in nutrient broth, the bactericidal activity in urine was less pronounced. The combination of cefazedone and gentamicin proved to be bactericidal in low concentrations.
Staphylococcus aureus, Bacteria, Drug Synergism, Microbial Sensitivity Tests, In Vitro Techniques, Cephalosporins, Culture Media, Escherichia coli, Humans, Gentamicins, Proteus mirabilis
Staphylococcus aureus, Bacteria, Drug Synergism, Microbial Sensitivity Tests, In Vitro Techniques, Cephalosporins, Culture Media, Escherichia coli, Humans, Gentamicins, Proteus mirabilis
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).5 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!