To explore the effect of thick and thin sputum on the restoration of oral anterior teeth and the index of gingival crevicular fluid.A study was conducted on 80 patients (130 teeth) who underwent full-ceramic crown treatment for anterior tooth restoration in Jiangnan University Affiliated Hospital 's oral clinic. The patients were divided into thick gingival type (42 cases, 67 teeth) and thin gingival type (38 cases, 63 teeth) according to their gingival biotype. The two groups were compared before and after the restoration with improved plaque index (mPI), modified bleeding index (mBI), probing depth (PD), clinical evaluation score of oral prosthesis, tumor necrosis factor-alpha (TNF-alpha) and IL-1 β(interleukin-1β) in gingival crevicular fluid. Statistical analysis was performed with SPSS 21.0 software package.Before treament, there were no significant differences in mPI, mBI and PD between the two groups (P＞0.05); 12 months after treament, mPI, mBI and PD of the thin gingiva group were significantly lower than those of the thick gingiva group(P＜0.05). Before treament, there were no significant differences in TNF-α and IL-1β levels in gingival crevicular fluid between the two groups(P＞0.05); 12 months after treament, TNF-α and IL-1β levels of the thin gingiva group were significantly lower than those of the thick gingiva group(P＜0.05). Six months after treament, there were no significant differences in prosthesis integrity, marginal adaptation, color matching, periodontal health status and secondary caries scores between the two groups (P＞0.05); 12 months after treament, the marginal adaptation, periodontal health status and secondary caries scores of the thick gingiva group were significantly higher than those of the thin gingiva group(P＜0.05); the marginal discoloration score of the thick gingiva group was significantly lower than that of the thin gingiva group at 6 months and 12 months after treament(P＜0.05).The thin sputum type is more conducive to repairing the oral cavity after treatment, and is beneficial to the maintenance of oral health condition after repair. The gingival index of the thick sputum type patient will be significantly increased after repair, and the risk of gingival inflammation is increased. The aesthetic effect is better than the thin sputum type.