
pmid: 38315532
pmc: PMC11925261
Noninvasive fetal blood group antigen genotyping serves as a diagnostic tool to predict the risk of hemolytic disease of the fetus and newborn in pregnancies of immunized women. In addition, fetal RHD genotyping is used as an antenatal screening to guide targeted use of immunoglobulin prophylaxis in non-immunized RhD negative, pregnant women. Based on testing of cell-free DNA extracted from maternal plasma, these noninvasive assays demonstrate high performance accuracies. Consequently, noninvasive fetal blood group antigen genotyping has become standard care in transfusion medicine.
Rh-Hr Blood-Group System, Genotyping Techniques, Genotype, Infant, Newborn, Immunohematology, Fetal Blood, Erythroblastosis, Fetal, Blood Grouping and Crossmatching, Pregnancy, Prenatal Diagnosis, Blood Group Antigens, Humans, Female, Cell-Free Nucleic Acids
Rh-Hr Blood-Group System, Genotyping Techniques, Genotype, Infant, Newborn, Immunohematology, Fetal Blood, Erythroblastosis, Fetal, Blood Grouping and Crossmatching, Pregnancy, Prenatal Diagnosis, Blood Group Antigens, Humans, Female, Cell-Free Nucleic Acids
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