The purpose of this workshop was to draw attention to one sector of research in modern psychosomatic medicine, "life events research". Nowadays it is relatively well documented that significant life events may increase an individual's susceptibility to the development of physical or psychic illness. "Life events research" is grounded on the stress concept, and in our practice is integrated into the bio-psycho-social approach. Bereavement, problems at work, disruption of deep rooted life habits, social isolation, family problems and poor socio-economic conditions are the most important of these events. Their impact depends on the real or symbolic meaning given to them, on the available coping mechanism, on the presence or absence of social support, and also on the stage in the life cycle at which the events occur. Some practical implications for the physician are discussed.