Thialysine utilization by thialysine resistant CHO cells.
Copyright policy )Thialysine utilization by thialysine resistant CHO cells.
Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.
Cricetulus, Cricetinae, Protein Biosynthesis, Drug Resistance, Animals, amino acids; analogs /&/ derivatives/metabolism/pharmacology; analysis; animals; cell line; cricetinae; cricetulus; cysteine; drug resistance; protein biosynthesis, Cysteine, Amino Acids, Cell Line
Cricetulus, Cricetinae, Protein Biosynthesis, Drug Resistance, Animals, amino acids; analogs /&/ derivatives/metabolism/pharmacology; analysis; animals; cell line; cricetinae; cricetulus; cysteine; drug resistance; protein biosynthesis, Cysteine, Amino Acids, Cell Line
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