Topological indices are valuable tools in predicting properties of chemical compounds. This study focuses on degree-based topological indices, which have shown strong correlations with various physico-chemical properties such as boiling points and strain energy. Specifically, we applied these indices to titania nanotubes [Formula: see text] and explored the vertex and edge versions of the Mostar index. These findings provide insights into the properties of [Formula: see text] nanotubes and contribute to the development of topological indices for predicting the behavior of other chemical compounds.