
The aim of this study was to evaluate the functional outcomes in terms of best-corrected visual acuity (BCVA) and visual field (VF) defects in optic nerve compression (thyroid eye disease-compressive optic neuropathy, TED-CON) patients after treatment.In this observational, retrospective study, the medical charts of 51 patients (96 eyes) with a diagnosis of definitive TED-CON between 2010-2020 were included.After the diagnosis of TED-CON, 16 patients (27 eyes) received steroid-pulse (medical) treatment alone, 67 eyes received an additional surgical orbital decompression, whereas 1 patient (2 eyes) refused both treatment methods. In 74 eyes (77.1%) we detected an improvement of the BCVA ≥ 2 lines after the treatment over a mean time interval of 31.7 weeks (with no significant difference between treatment methods). In 22 eyes (27.2%) out of the 81 that underwent a posttreatment VF examination, we observed a complete resolution of the defects over a mean time interval of 39.9 weeks. When we limited analysis to patients with a minimum follow-up of 6 months at last visit, we found 33 eyes (61.1%) out of 54 eyes still had a VF defect.In our data, more than half of the TED-CON cases (61.5%) had a good prognosis with a final BCVA ≥ 0.8 at the last visit; however, only 22 eyes (27.2%) showed a complete resolution of VF defects, while 33 eyes (61.1%) had residual defects measured after a minimum follow-up of 6 months. These results suggest that while the BCVA recovers relatively well, the VF of patients is likely to remain marked by optic nerve compression.
Graves Ophthalmopathy, Arthrogryposis, Nerve Compression Syndromes, Optic Nerve Diseases, Visual Acuity, Vision Disorders, Humans, Optic Nerve, Hereditary Sensory and Motor Neuropathy, Retrospective Studies
Graves Ophthalmopathy, Arthrogryposis, Nerve Compression Syndromes, Optic Nerve Diseases, Visual Acuity, Vision Disorders, Humans, Optic Nerve, Hereditary Sensory and Motor Neuropathy, Retrospective Studies
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