
Pleural fluid lactate (PFL) and blood lactate (BL) concentrations were simultaneously measured in samples from 46 patients with pleural effusion. PFL exceeded 6 mmol/l in all 15 patients with pyogenic bacterial pleurisy but in only 5 of the other 31 patients. We have found that a PFL-BL difference greater than or equal to 6 mmol/l has a sensitivity of 100% and a specificity of 93.8% in detecting pyogenic pleural effusions. Results are available within 1 h of sample collection, so that PFL-BL difference may become a useful aid in the early assessment of pleural effusions.
Diagnosis, Differential, Pleural Effusion, Pleural Neoplasms, Lactates, Humans, False Positive Reactions, Bacterial Infections, Tuberculosis, Pleural, Empyema
Diagnosis, Differential, Pleural Effusion, Pleural Neoplasms, Lactates, Humans, False Positive Reactions, Bacterial Infections, Tuberculosis, Pleural, Empyema
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