Shikimic acid and quinic acid are not mutagenic in the Ames assay.

Shikimic acid, reported to cause tumors in mice, and its close structural analog, quinic acid, both ubiquitous constituents of higher plants, were found not be be mutagenic in the Ames assay when tested with and without the rat liver microsomal activation system.

Keywords

Salmonella typhimurium, Microsomes, Liver, Quinic Acid, Animals, Shikimic Acid, In Vitro Techniques, Mutagens, Rats

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