
D-penicillamin is widely used for the treatment of various diseases, such as cystinuria. Wilson's disease or rheumatoid arthritis. It is an osteolathyrogenic agent. This effect may explain some side-effects such as fetal dysplasias, wound healing defects, skin lesions, obliterative bronchiolitis, auto-immune abnormalities. Conversely the collagen effects of D-Penicillamin explain its use in various fibrosis states such as progressive systemic sclerosis, liver or lung fibrosis.
Liver Cirrhosis, Scleroderma, Systemic, Pulmonary Fibrosis, Penicillamine, Collagen Diseases, Bronchi, Skin Diseases, Arthritis, Rheumatoid, Cicatrix, Hepatolenticular Degeneration, Aminopropionitrile, Humans, Collagen, Procollagen, Autoantibodies
Liver Cirrhosis, Scleroderma, Systemic, Pulmonary Fibrosis, Penicillamine, Collagen Diseases, Bronchi, Skin Diseases, Arthritis, Rheumatoid, Cicatrix, Hepatolenticular Degeneration, Aminopropionitrile, Humans, Collagen, Procollagen, Autoantibodies
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