
To compare maternal and perinatal outcomes in pregnancies with transient and persistent idiopathic polyhydramnios to those with normal amniotic fluid volume.This retrospective cohort study included subjects delivering a singleton pregnancy between January 1, 2015, and June 30, 2020, with sonography ≥26 weeks' gestation demonstrating transient or persistent idiopathic polyhydramnios (amniotic fluid index [AFI] ≥24.0 cm) or normal AFI (referent group). The primary maternal outcome was a composite of spontaneous preterm delivery 4500 g, fetal or neonatal death, 5-minute Apgar score 24 hours.Patients with transient polyhydramnios (n = 259) exhibited maternal outcomes similar to those of the referent group (n = 435) but had significantly increased odds for the primary perinatal outcome (odds ratio [OR] 1.70, 95% confidence interval [CI] 1.15-2.53; P = .008) and for birthweight ≥4500 g (OR 8.70, 95% CI 1.89-40.0; P = .005). Persistent polyhydramnios (n = 176) was significantly associated with both the primary maternal (OR 1.93, 95% CI 1.27-2.95, P = .002) and primary perinatal outcome (OR 2.15, 95% CI 1.40-3.30; P 4500 g. Persistent polyhydramnios is associated with both adverse maternal and perinatal outcomes.
Polyhydramnios, Pregnancy, Infant, Newborn, Pregnancy Outcome, Humans, Birth Weight, Female, Amniotic Fluid, Retrospective Studies
Polyhydramnios, Pregnancy, Infant, Newborn, Pregnancy Outcome, Humans, Birth Weight, Female, Amniotic Fluid, Retrospective Studies
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