An existential analysis of the story that patients make related to the experience of suffering from cancer is presented. The objective of the study was to observe, describe and understand the way in which suffering reveals the temper of anguish and with it, the possibility of an authentic existence. Although this study only analyzes the report of two patients, the complete sample consists of 25 patients, all adults, of both sexes, aged between 40 and 70 years. The type of cancer varied, but in all cases it was treated with surgery, chemotherapy, and radiation therapy. Participation was voluntary and with consent. The interpretation and analysis was done by confronting the hermeneutical theories with the life stories of the patients.