Dosage of the Sts gene in the mouse.
Copyright policy )Dosage of the Sts gene in the mouse.
In this study we compared steroid sulfatase levels in XO, XX, and XY mice and carried out a clonal analysis in fibroblast cell cultures from mice heterozygous for the steroid sulfatase deficiency gene and heterozygous at the X-linked electrophoretic phosphoglycerate kinase locus. The combined results indicate that the murine steroid sulfatase locus is not dosage compensated and is not subject to X-inactivation. With respect to X-inactivation, it behaves in a somewhat different way from the closely linked sex-reversed gene and the human steroid sulfatase locus.
Male, Mice, Inbred BALB C, Mice, Inbred C3H, X Chromosome, Genetic Linkage, Mice, Dosage Compensation, Genetic, Y Chromosome, Animals, Female, Steryl-Sulfatase, Sulfatases, Alleles
Male, Mice, Inbred BALB C, Mice, Inbred C3H, X Chromosome, Genetic Linkage, Mice, Dosage Compensation, Genetic, Y Chromosome, Animals, Female, Steryl-Sulfatase, Sulfatases, Alleles
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